Current Advances in the Diagnosis and Treatment of Nonerosive Reflux Disease

Table 1

Classification of patients with reflux symptoms.

Classification	Distal esophageal acid exposure	Symptom correlation	Symptom response to PPI
Erosive esophagitis	Increased	(+)	Good
Barrett’s esophagus	Increased	(+)	Good
NERD
Acid reflux related	Increased	(+)	Good
Weakly acid related	Not increased	(+)	Moderate*
Nonacid related	Not increased	(+)	Poor*
Functional heartburn	Not increased	(−)	Poor

∗Not well investigated.