Study of RNA Interference Targeting NET-1 Combination with Sorafenib for Hepatocellular Carcinoma Therapy <i>In Vitro</i> and <i>In Vivo</i>

<table>The expression mRNA levels of caspase 3, caspase 8, and caspase 9 of tumor tissues in NET-1shRNA, sorafenib, combination, and untreated groups. RT-QPCR showed that in NET-1shRNA, sorafenib, and combination groups caspase 3 mRNA levels increased by 2.99, 1.89, and 4.18 times, Caspase 8 mRNA levels increased by 2.14, 1.31 and 2.47 times, and Caspase 9 mRNA levels increased by 1.15, 1.91, and 1.99 times, compared with untreated group, respectively. (<sup>●</sup><svg height="11.375" id="M25" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with untreated group, *<svg height="11.375" id="M26" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 58.712502 11.375" width="58.712502" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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</svg> compared with combination group).</table>

Gastroenterology Research and Practice

fig7

Figure 7

Figure 7: Study of RNA Interference Targeting NET-1 Combination with Sorafenib for Hepatocellular Carcinoma Therapy <i>In Vitro</i> and <i>In Vivo</i> 

Gastroenterology Research and Practice

Study of RNA Interference Targeting NET-1 Combination with Sorafenib for Hepatocellular Carcinoma Therapy In Vitro and In Vivo

Figure 7