Research Article
Expression of Potential Cancer Stem Cell Marker ABCG2 is Associated with Malignant Behaviors of Hepatocellular Carcinoma
Table 2
Difference of tumorigenic ability between ABCG2+ and ABCG2− cells.
| | Cell phenotype | Cell number |
Number of tumors established/total number of mice inoculated
(maximum diameter of tumors (cm)) | | 1 week | 2 weeks | 4 weeks | 8 weeks |
| | ABCG2+ | | 4/4 (0.4–0.6) | 4/4 (0.8–1.2) | 3/3 (1.6–2.0) | 2/2 (1.7–2.1) | | 4/4 (0.3–0.5) | 4/4 (0.7–1.0) | 4/4 (1.2–1.9) | 4/4 (0.7–2.0) | | 4/4 (0.1–0.3) | 4/4 (0.5–0.9) | 4/4 (1.0–1.4) | 4/4 (1.2–1.5) | | 1/4 (0.2) | 4/4 (0.5–0.8) | 4/4 (0.9–1.3) | 3/3 (1.0–2.2) | | 0/4 | 2/4 (0.2–0.5) | 4/4 (0.5–1.0) | 4/4 (0.6–1.6) |
| | ABCG2− | | 4/4 (0.2–0.4) | 4/4 (0.8–1.1) | 4/4 (1.2–1.9) | 2/2 (1.3–1.8) | | 4/4 (0.2-0.3) | 4/4 (0.7–1.0) | 4/4 (1.2–1.8) | 3/3 (1.3–2.0) | | 0/4 | 3/4 (0.4–0.6) | 4/4 (0.6–1.3) | 4/4 (0.6–2.5) | | 0/4 | 0/4 | 0/4 | 1/4 (0.8) | | 0/4 | 0/4 | 0/4 | 0/4 |
|
|
