MicroRNA-429 Modulates Hepatocellular Carcinoma Prognosis and Tumorigenesis
Figure 4
MiR-429 expression modified the proliferation and the apoptosis of HCC cancer cells. According to the types of mimics transfected, cell lines were divided into four groups: control group (Control, by null mimics), mock group (Mock, by mock mimics) miR-429 group (miR-429, by mature miR-429 mimics), and inhibitor group (Inhibitor, by inhibitor of mature miR-429). (a) Association between miR-429 expression and cancer cell proliferation was elucidated using the 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT) reduction assays. (b) Relationship between miR-429 expression and cancer cell apoptosis was evaluated by flow cytometry technique. Data were analyzed using one-way ANOVA with Bonferroni corrections. *.
