Research Article

Histological Distinction between the Granular and Nongranular Types of Laterally Spreading Tumors of the Colorectum

Figure 3

Estimation of submucosal vascular density of laterally spreading tumors (LSTs): all the vessels ≥5 μm in diameter were counted and arterioles and venules were distinguished. (a) A typical case of LST-nongranular (LST-NG) type with higher vascular density (56.3 vessels/mm²) than (b) a LST-granular (LST-G) type with 31.7 vessels/mm². (c) The double staining with Factor VIII + Elastica van Gieson has facilitated the identification of arterioles and venules for LST-NG and for (d) LST-G, original magnification ×20.
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