Absence of Autophagy-Related Proteins Expression Is Associated with Poor Prognosis in Patients with Colorectal Adenocarcinoma

Table 1

Baseline clinicopathological characteristics of patients with colorectal cancer.

Characteristics	Total
	Patient number	%
Patient number	263
Age (years), median (range)	64 (30–83)
<65	141	53.6
≥65	122	46.4
Gender
Male	141	53.6
Female	122	46.4
Histology
Tubular adenocarcinoma	233	88.6
Others*	30	11.4
T stage
1	1	0.4
2	51	19.4
3	163	62.0
4	48	18.2
N stage
0	114	43.3
1	80	30.4
2	69	26.2
Stage
I	38	14.4
II	67	25.5
III	101	38.4
IV	57	21.7
Histological grade
Well/moderately	222	84.4
Poorly	41	15.6
Lymphovascular invasion
Negative	99	37.6
Positive	164	62.4
Site of primary tumor
Right colon	69	26.2
Left colon	83	31.6
Rectum	111	42.2
Curative resection (R0 resection)
Yes	208	79.1
No	55	20.9
Adjuvant therapy (𝑛=120)
5-FU-based chemotherapy	74	28.1
5-FU-based CCRT	46	17.5

∗Mucinous carcinoma (𝑛=28), signet-ring-cell carcinoma (𝑛=2).
Data are numbers of patients with percentages in parentheses unless otherwise specified.
SD: standard deviation; T1: tumor invades submucosa; T2: tumor invades muscularis propria; T3: tumor invades through the muscularis propria into the subserosa or into the nonperitonealized pericolic or perirectal tissues; T4: tumor perforates the visceral peritoneum or directly invades other organs; N1: metastasis in 1–3 pericolic or perirectal lymph nodes; N2: metastasis in >3 pericolic or perirectal lymph nodes; 5-FU: 5-fluorouracil, CCRT: concurrent chemoradiation therapy.