Research Article
ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?
Table 2
Genotypic frequency in the whole study population.
| | Genotypes | NOR ()
(freq.%) | MAL ()
(freq.%) | OR (95% CI) | value |
| | ABCB1 G2677T/A | | | 0.29 (0.11~0.79) | 0.015 | | GG | 27 (35.5) | 28 (36.8) | TT versus (GT+GG) | | | GT | 31 (40.8) | 38 (50.0) | | | | TT | 18 (23.7) | 6 (7.9) | | | | TA | 0 (0) | 2 (2.6) | | | | GA | 0 (0) | 2 (2.6) | | | | ABCB1 C3435T | | | 0.35 (0.15~0.80) | 0.013 | | CC | 22 (28.9) | 21 (27.6) | TT versus (CT+CC) | | | CT | 31 (40.8) | 45 (59.2) | | | | TT | 23 (30.3) | 10 (13.2) | | | | ABCC1 G-260A | | | 1.49 (0.62~3.60) | 0.376 | | GG | 10 (13.2) | 14 (18.4) | GG versus (GA+AA) | | | GA | 35 (46.0) | 32 (42.1) | | | | AA | 31 (40.8) | 30 (39.5) | | | | ABCG2 C421T | | | 5.13 (0.24~108.70) | 0.294 | | CC | 61 (80.3) | 62 (81.6) | TT versus (CT+CC) | | | CT | 15 (19.7) | 12 (15.8) | | | | TT | 0 (0) | 2 (2.6) | | |
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