Table 1: Clinicopathological characteristics associated with CIMP status.

CIMP−CIMP+ value
 
 
No. (%)No. (%)

Age (yr)0.270
 Mean ± SD
Sex0.750
 Male17 (44.7)6 (50.0)
 Female21 (55.3)6 (50.0)
Sitea0.046
 Proximal5 (13.2)5 (41.7)
 Distal33 (86.8)7 (58.3)
Stage0.022
 II17 (44.7)1 (8.3)
 III21 (55.3)11 (91.7)
Histology0.059
 Adenocarcinoma32 (84.2)7 (58.3)
 Mucinous adenocarcinoma6 (15.8)5 (41.7)
Grade0.007
 Well/moderate31 (81.6)5 (41.7)
 Poor7 (18.4)7 (58.3)
Lymphovascular invasion0.121
 Present3 (8.1)3 (25.0)
 Absent34 (91.9)9 (75.0)
Perineural invasion0.961
 Present3 (7.9)1 (8.3)
 Absent35 (92.1)11 (91.7)
CEA level0.802
 Normal28 (80.0)10 (83.3)
 Elevated7 (20.0)2 (16.7)
Adjuvant chemotherapy0.637
 Not received10 (26.3)4 (33.3)
 Received28 (73.7)8 (66.7) 

SD: standard deviation, CIMP: CpG island methylator phenotype, CEA: carcinoembryonic antigen.
aProximal location included the cecum, ascending colon, hepatic flexure of colon, and transverse colon while distal location included the splenic flexure of colon, descending colon, sigmoid colon, and rectum.