Clinical Characteristics and Surgical Prognosis of Hepatocellular Carcinoma with Bile Duct Invasion
Table 3
Univariate analysis of risk factors for prognosis of HCC after surgical resection.
Variables
Median survival (m)
value
Age (≤40/>40 yr)
96/317
28.4/30.6
0.475
Gender (male/female)
333/80
30.4/28.3
0.423
Virus status
HBV/HCV/none
312/7/94
32.0/30.2/29.5
0.210
Child-Pugh classification
A/B
301/112
33.6/30.0
0.456
Liver cirrhosis (+/−)
272/141
29.3/31.4
0.512
Hemoglobin (<110/≥110 g/L)
62/351
32.7/34.3
0.666
Platelet count (×109/L) (<100/≥100)
194/219
33.1/27.3
0.012
ALT (≤40/>40 U/L)
195/218
33.5/27.4
0.013
AST (≤40/>40 U/L)
139/274
37.9/26.3
<0.001
TBIL (≤17.1/>17.1 umol/L)
228/185
29.6/30.4
0.870
Albumin(<35/≥35 g/L)
320/93
31.3/27.0
0.153
PT (<14/≥14 s)
278/135
29.6/31.0
0.580
AFP (<20/≥20 ng/mL)
118/295
37.3/27.2
<0.001
Tumor size (<5/≥5 cm)
227/186
37.2/21.4
<0.001
tumor number (1/≥2)
317/96
33.3/19.2
<0.001
Capsule formation (+/−)
286/127
33.7/21.8
<0.001
Bile duct invasion (B−/B1/B2)
378/28/7
31.1/14.6/39.0
0.001
Portal vein invasion (+/−)
48/365
14.6/32.2
<0.001
Surgical margin (<1/≥1 cm)
198/215
31.9/28.7
0.153
Blood transfusion (≤600/>600 mL)
196/217
36.7/24.4
<0.001
Hepatocellular carcinoma; HBV: hepatitis B virus, AFP: alpha-fetoprotein, TBIL: total bilirubin, ALT: alanine aminotransferase; AST: aspartate aminotransferase; ALB: albumin; PT: prothrombin time. The bold value means “” or “statistically different”.
