Table 2: Analysis of risk factors for metachronous gastric tumors according to Cox’s proportional hazards model.

FactorsNo.Univariate analysis
Hazard ratio95% CI

Age (1-year increment)1.000.97–1.04
Gender
 Male2721
 Female850.360.11–0.89
Tumor size (increment of 1 mm)1.010.98–1.03
Location
 Upper third381
 Middle third 911.680.55–7.29
 Lower third2281.020.35–4.32
Gross type
 Elevated1611
 Depressed1961.070.57–2.04
Gastric mucosal atrophy
 Closed 301
 Open3271.200.43–4.99
Synchronous tumor
 Negative 3071
 Positive501.260.47–2.79
Histology
 Intestinal3311
 Diffuse260.840.20–2.33
Depth
 Mucosa3261
 Submucosa311.050.25–2.92
Serum gastrin
 ≤100 pg/mL 941
 >100 pg/mL1870.580.28–1.21
Serum pepsinogen
 Negative1111
 Positive1701.230.59–2.75

CI: confidence interval.
Serum pepsinogen-positive: PG I ≤ 70 ng/mL and PG I/II ≤ 3.