Research Article
Characteristics of Metachronous Gastric Tumors after Endoscopic Submucosal Dissection for Gastric Intraepithelial Neoplasms
Table 2
Analysis of risk factors for metachronous gastric tumors according to Cox’s proportional hazards model.
| Factors | No. | Univariate analysis | Hazard ratio | 95% CI |
| Age (1-year increment) | | 1.00 | 0.97–1.04 | Gender | | | | Male | 272 | 1 | | Female | 85 | 0.36 | 0.11–0.89 | Tumor size (increment of 1 mm) | | 1.01 | 0.98–1.03 | Location | | | | Upper third | 38 | 1 | | Middle third | 91 | 1.68 | 0.55–7.29 | Lower third | 228 | 1.02 | 0.35–4.32 | Gross type | | | | Elevated | 161 | 1 | | Depressed | 196 | 1.07 | 0.57–2.04 | Gastric mucosal atrophy | | | | Closed |
30 | 1 | | Open | 327 | 1.20 | 0.43–4.99 | Synchronous tumor | | | | Negative | 307 | 1 | | Positive | 50 | 1.26 | 0.47–2.79 | Histology | | | | Intestinal | 331 | 1 | | Diffuse | 26 | 0.84 | 0.20–2.33 | Depth | | | | Mucosa | 326 | 1 | | Submucosa | 31 | 1.05 | 0.25–2.92 | Serum gastrin | | | | ≤100 pg/mL | 94 | 1 | | >100 pg/mL | 187 | 0.58 | 0.28–1.21 | Serum pepsinogen | | | | Negative | 111 | 1 | | Positive | 170 | 1.23 | 0.59–2.75 |
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CI: confidence interval. Serum pepsinogen-positive: PG I ≤ 70 ng/mL and PG I/II ≤ 3.
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