Synchronized Dual Pulse Gastric Electrical Stimulation Induces Activation of Enteric Glial Cells in Rats with Diabetic Gastroparesis

<table>Immunohistochemical staining of S100B in the enteric plexus of stomach. Tissues with brown deposits were positive reaction. (a) S100B expression in ECN, EDM, EDM + ASGES, and EDM + CSGES. (b) S100B expression in TCN, TDM, TDM + ASGES, and TDM + CSGES. (c) Semiquantification of S100B-positive cells in each group. There were no significant differences between ECN and EDM. The expression of S100B in TDM and TCN groups was lower than in EDM and ECN groups, respectively. ASGES and CSGES had little effect on the expression of S100B in EDM. Comparing with TDM group, the immunopositive stain was decreased significantly in TDM group. But the immunopositive stain significantly increased after ASGES and CSGES. Data are presented as means ± SD. <svg height="13.95" id="M57" style="vertical-align:-0.30096pt" version="1.1" viewbox="0 0 66.324997 13.95" width="66.324997" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
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Gastroenterology Research and Practice

fig5

Figure 5

Figure 5: Synchronized Dual Pulse Gastric Electrical Stimulation Induces Activation of Enteric Glial Cells in Rats with Diabetic Gastroparesis 