Research Article
Epigenetic-Mediated Downregulation of μ-Protocadherin in Colorectal Tumours
Table 1
Patients’ characteristics.
| | Expression qRTPCR | Expression IHC | DNA methylation pyrosequencing |
| Cancer patients | | | | Number of patients | 26 | 14 | 24 | Sex (number of patients) | | | | Male | 11 | 6 | 10 | Female | 15 | 8 | 14 | Age (years) | | | | Range | 38–82 | 38–78 | 38–82 | Median | 64 | 67 | 63.5 | Astler-Coller’s stage (number of patients) | | | | B1 | 4 | 3 | 4 | B2 | 15 | 8 | 13 | C2 | 7 | 3 | 7 | Adenoma patients | | | | Number of patients | 42 | 12 | 12 | Sex (number of patients) | | | | Male | 25 | 6 | 6 | Female | 17 | 6 | 6 | Age (years) | | | | Range | 41–83 | 42–80 | 42–80 | Median | 60 | 61.5 | 61.5 | Size (mm) | | | | Range | 9–50 | 10–50 | 10–50 | Median | 15 | 16 | 16 | Histopathology (number of patients) | | | | Tubular AD | 29 | 5 | 5 | Tubulovillous AD | 13 | 7 | 7 | Normal mucosa | | | | Number of samples | 24 | 14 | 10 |
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