Review Article
Therapeutic Targeting of Fibroblast Growth Factor Receptors in Gastric Cancer
Table 3
Clinical trials of FGFR-targeting agents in GC.
| | Agent | Target | Type of cancer | Phase | Combined regimen | Status | Reference |
| | Dovitinib (TKI258) | FGFR, VEGFR, PDGFR, FLT-3, KIT, and CSF-1 | Gastric (scirrhous type) | II | None | Ongoing | [55] | | Gastric (FGFR2 amplification) | II | None | Ongoing | [56] |
| | AZD4547 |
FGFR and VEGFR | Gastric | II | Docetaxel | Ongoing | [57] | | Gastric (FGFR2 amplification) | II | Paclitaxel | Ongoing | [58] |
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