The Increased Expression of CCL20 and CCR6 in Rectal Mucosa Correlated to Severe Inflammation in Pediatric Ulcerative Colitis

Figure 1

Immunohistochemical findings for CCL20 in the rectal mucosa. CCL20 expression was observed in the nucleus of epithelial cells, inflammatory cells, and lymphoid follicles. Different grades of CCL20 intensity in epithelial cells were evaluated as follows: grade 0 (negative, (a)), 44 specimens; grade 1 (weak, (b)), 37 specimens; grade 2 (moderate, (c)), 48 specimens, and grade 3 (severe, (d)), 12 specimens, respectively. Original magnification, 100x.

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