Review Article
MicroRNAs in Pancreatic Cancer: Involvement in Carcinogenesis and Potential Use for Diagnosis and Prognosis
Table 4
Types of samples used for miRNA analysis in pancreatic cancer.
| ā | Serum | Fine needle biopsy | Resected tissue |
| Invasiveness | Low | Medium | High | Possible sampling frequency | Days | Days-weeks | Mostly no or only one sampling | The amount of sample/target miRNA | Sufficient/very small | Small/small | Sufficient/sufficient | The possibility of obtaining pure tumor tissue (cells) | No | Yes (microdissection) | Yes (macrodissection, microdissection) | Respective references | [54, 58, 68, 84ā86] | Fixation [62, 67, 89] RNA stabilization solution [67, 74] | Frozen tissue [53, 56, 61, 63, 70, 72, 76, 97] Fixation [59, 67, 78, 84, 90, 96] |
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