A Comparison of Short- and Long-Term Therapeutic Outcomes of Infliximab- versus Tacrolimus-Based Strategies for Steroid-Refractory Ulcerative Colitis

Table 2

Cox proportional hazard model for relapse in IFX group.

Parameter	Multivariate analysis (Cox proportional hazard model)
	HR	95% CI	value
Sex			0.65
Male	1
Female	0.69	0.097–3.28
Age at start of the treatment (y)			0.23
20	1
20	1.64 × 10^−9	0–3.89
Disease duration at the treatment (y)			0.012
5	1
5	9.17	1.54–181.6
Disease Extension			0.33
Left-sided colitis	1
Extensive colitis	2.69	0.42–52.1
Response to corticosteroids
Dependence	1
Refractory	0.89	0.11–5.81	0.91
Others	9.01 × 10^−9	0–34.7	0.56
Concomitant use of thiopurine			0.74
Yes	1
No	1.36	0.21–10.6
Withdrawal of infliximab			0.2
No	1
Yes	2.07 × 10^−9	1.15 × 10^−26–4.00

HR, hazard ratio; CI, confidence interval.