Reducing the Social Gradient in Uptake of the NHS Colorectal Cancer Screening Programme Using a Narrative-Based Information Leaflet: A Cluster-Randomised Trial

Table 2

Proportion of individuals invited who were adequately screened^†, according to gender, age, IMD quintile^‡, hub, and screening round.

	SI	SI + N	Adjusted odds ratio	value
	% ()	% ()	(95% CI)
Total	58.5 (44,904)	56.7 (41,822)	1.00 (0.96–1.03)	0.80
Gender
Female	60.9 (23,811)	59.3 (22,499)	1.01 (0.96–1.05)	0.77
Male	56.1 (21,093)	54.0 (19,323)	0.98 (0.94–1.03)	0.50
Age (median split)
<65 years	55.2 (19,014)	53.3 (18,264)	1.01 (0.97–1.05)	0.67
≥65 years	61.2 (25,890)	59.7 (23,558)	0.98 (0.92–1.04)	0.45
IMD quintile
1st quintile (0–8.49, least deprived)	66.8 (11,411)	64.6 (11,005)	0.98 (0.93–1.04)	0.57
2nd quintile (8.50–13.79)	62.7 (11,080)	62.1 (10,253)	1.00 (0.94–1.06)	0.91
3rd quintile (13.80–21.35)	59.4 (9,601)	58.3 (8,911)	1.05 (0.97–1.13)	0.24
4th quintile (21.36–34.17)	52.9 (7,083)	50.7 (6,535)	1.00 (0.94–1.06)	0.95
5th quintile (34.18–87.80, most deprived)	46.0 (5,580)	42.4 (4,966)	0.92 (0.86–0.98)	0.02
Hub
Midlands and North West	57.6 (12,163)	53.4 (11,439)	0.95 (0.88–1.03)	0.22
Southern	60.2 (10,069)	61.5 (12,712)	1.00 (0.91–1.10)	0.98
London	49.2 (4,327)	45.4 (3,864)	1.00 (0.95–1.05)	0.95
North East	60.8 (7,837)	59.1 (7,716)	0.98 (0.90–1.06)	0.56
Eastern	61.2 (10,508)	60.5 (6,091)	1.07 (0.99–1.16)	0.08
Screening round
Prevalent first time invitees	49.8 (6,231)	50.2 (7,678)	1.03 (0.99–1.08)	0.14
Prevalent previous nonresponders	14.3 (3,284)	14.0 (3,113)	0.97 (0.90–1.04)	0.35
Incident episodes	85.7 (35,389)	85.6 (31,031)	0.99 (0.94–1.04)	0.64

SI: standard information; SI + N: standard information plus narrative leaflet
^†Returned a gFOBt kit (or kits) within 18 weeks of being sent the invitation, with a definitive “normal” (no further investigation required) or “abnormal” (requiring referral for further investigation, usually colonoscopy) screening test result available at the time of data extraction.
^‡546 (274 SI and 272 SI + N) individuals missing an IMD score, 301 of these were adequately screened (149 SI and 152 SI + N).