Ex Vivo Apoptosis in CD8+ Lymphocytes Predicts Rectal Cancer Patient Outcome

Figure 1

Evaluation of apoptotic and necrotic rates of CD8+ cells with the cell analysis software Kaluza, showing an example of (a) untreated samples, (b) samples treated with 2 Gy ionizing radiation, (c) samples treated with 8 Gy ionizing radiation, and (d) samples treated with 2 Gy ionizing radiation combined with 10 μg/mL Oxaliplatin. (e) Apoptotic (white bars) and necrotic (grey bars) rates in percentages by treatment and lymphocyte subgroups CD4+ and CD8+ of 87 rectal cancer patients. Control values represent the apoptotic or necrotic background and were subtracted from the values of the treated samples. Significantly different values were marked by three asterisks ().

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