Formulation for Effective Screening and Management of Nonalcoholic Steatohepatitis: Noninvasive NAFLD Management Strategy

Table 2

Univariate comparison between SS and NASH suspects.

	SS suspects		NASH suspects		Probability
	Median	IQR	Median	IQR
Age (years)	66	61–72	59	50–72	0.014
Gender (male : female)	12 : 17		28 : 48		0.67
Body mass index (kg/m^2)	24.4	22.9–26.3	26.8	24.4–30.5	0.0016
T2DM (yes : no)	10 : 19		36 : 40		0.23
Hypertension (yes : no)	14 : 15		36 : 40		0.93
Albumin (g/dL)	4.4	4.2–4.6	4.3	3.9–4.5	0.13
ALT (IU/L)	37	21–55	43	27–82	0.19
AST/ALT	0.80	0.60–1.15	1.17	0.74–1.54	0.011
ALP (IU/L)	252	202–290	292	202–365	0.14
γ-GTP (IU/L)	46	24–104	60	40–126	0.014
Total bilirubin (mmol/L)	12.9	10.3–18.8	15.4	13.7–20.5	0.032
Triacylglycerol (mmol/L)	1.43	0.84–1.80	1.31	0.98–1.82	0.76
Total cholesterol (mmol/L)	5.14	4.72–5.59	4.73	4.16–5.40	0.085
Platelet count (×10^9/L)	207	191–264	159	115–194	<0.0001
VTTQ (m/sec)	1.15	1.07–1.24	2.20	1.67–2.92	<0.0001

SS: simple steatosis; NASH: nonalcoholic steatohepatitis; IQR: interquartile range; T2DM: type 2 diabetes mellitus; AST: aspartate aminotransferase; ALT: alanine aminotransferase; ALP: alkaline phosphatase; GTP: glutamyl transpeptidase; VTTQ: virtual touch tissue quantification.