Synergistic Effects of Simvastatin and Irinotecan against Colon Cancer Cells with or without Irinotecan Resistance

Figure 1

Effect of simvastatin or irinotecan alone on cell viability in HT-29 cell. Human colon cancer cells HT-29 were treated with serial concentrations of simvastatin (SV) and irinotecan (IR) for 48 h in 96-well plates, and cell viability was measured by MTT assay, respectively (a, b). The data are expressed as the means ± SD from three independent experiments. , compared to untreated control cells.

(a)

(b)