Research Article

Distinct Clinic-Pathological Features of Early Differentiated-Type Gastric Cancers after Helicobacter pylori Eradication

Table 1

Clinic-pathological characteristics of EGC lesions among eradication and control groups.

Variables Eradication group Control group p value
(51 lesions)(131 lesions)

Median age (range)74 (53–89)72 (53–92)0.29
Male % ()74.5% (38)81.7% (107)0.28
Location: U/M/L % ()21.6%/41.2%/37.2%10.7%/40.5%/48.8% 0.12
(11/21/19)(14/53/64)
Morphology: protruding/depressed % ()11.2%/88.2% 42.7%/57.3%<0.0001
(6/45) (56/75)
Color: redness/whiteness/same as surroundings % ()88.2%/7.8%/3.9%54.9%/28.2%/16.7% 0.0001
(45/4/2)(72/37/22)
Tumor size: ±SE11.7 ± 1.0 mm13.5 ± 0.6 mm0.0095
Depth: M/SM1/SM2 % ()90.1%/0%/9.9% 90.8%/5.3%/3.8% 0.077
(46/0/5)(119/7/5)
Unexpected SM2 case8.7% (4/46)2.4% (3/124)0.0867

Protruding, 0-I and 0-IIa; depressed, 0-IIc, 0-IIa + IIc, and 0-IIc + IIa according to the Japanese classification.
SM1, cases with submucosal invasion less than 500 μm; SM2, cases with submucosal invasion greater than 500 μm.
Patients whose SM2 invasion could not be expected before ESD.
Age and tumor size were compared using Mann-Whitney test.
Location, morphology, color, depth, and unexpected SM2 case were compared using chi statistics.