The Association between Helicobacter pylori Infection and Chronic Hepatitis C: A Meta-Analysis and Trial Sequential Analysis

Table 1

Characteristics of included studies.

Study	Country	NOS stars	H. pylori detection method	H. pylori positivity/total subjects		H. pylori positivity in different HCV progression stages
				Control	HCV	Noncirrhosis	Cirrhosis	HCC
Catéra et al. 2006 [15]	France	7	16sRNA PCR test	4/26	12/53	7/41	5/12	NR
Esmat et al. 2012 [16]	Egypt	6	16sRNA PCR test	1/11	29/74	8/41	9/17	12/16
Furusyo et al. 2011 [17]	Japan	8	Serological test	158/228	67/76	47/53	20/23	NR
Lönngren et al. 2009 [18]	Sweden	7	Serological test	7/40	19/38	NR	NR	NR
Pellicano et al. 2000 [19]	Italy	6	Serological test	275/463	226/254	NR	226/254	NR
Ponzetto et al. 2000 [20]	Italy	8	Serological test	183/310	54/70	NR	54/70	NR
Ponzetto et al. 2003 [21]	Italy	7	Serological test	291/619	131/179	96/135	35/44	NR
Rocha et al. 2005 [22]	France	6	16sRNA PCR test	1/24	37/85	1/29	17/25	19/31
Shang-Wei  et al. 2008 [23]	China	8	Serological test	59/136	118/188	70/126	26/34	22/28
Wei-ming 2013 [24]	China	6	Serological test	66/147	67/104	42/73	25/31	NR
Yong-Gui et al. 2008 [25]	China	7	Serological test	142/327	177/282	105/189	39/51	33/42
Leone et al. 2003 [26]	Italy	7	Serological test	25/46	36/46	NR	NR	36/46

NR: not reported; HCV: hepatitis C virus; HCC: hepatocellular carcinoma; NOS: Newcastle-Ottawa Scale.