Review Article
The Effect of Hepatosteatosis on Response to Antiviral Treatment in Patients with Chronic Hepatitis B: A Meta-Analysis
Table 1
Characteristics of the studies included in this meta-analysis.
| Study | Year | Location | Sample size | Number included in the analysis | Age-matched | Sex-matched | Follow-up (weeks) | Therapy regimen | Therapy period | Diagnosis method | Quality scores |
| Cindoruk et al. [16] | 2002–2006 | Turkey | 140 | 98 | Yes | Yes | 48 | Peg-IFN alfa-2a 180 μg/week or Peg-IFN alfa-2b 80 μg/week and LAM 100 mg/d | 48 | Histopathology | 7 | Ates et al. [13] | 2006–2009 | Turkey | 84 | 84 | No | Yes | 96 | Peg-IFN alfa-2a 180 μg/week or Peg-IFN alfa-2b 80 μg/week | 48 | Histopathology | 6 | Shi et al. [19] | 2007-2008 | China | 120 | 96 | No | Yes | 48 | Peg-IFN alfa-2a 180 μg/week or Peg-IFN alfa-2b 80 μg/week | 48 | Histopathology | 6 | Jin et al. [18] | 2007–2009 | China | 267 | 213 | Yes | Yes | 96 | ETV 0.5 mg/d | 96 | Ultrasound | 9 | Chen et al. [14] | 2007–2009 | China | 332 | 316 | Yes | Yes | 96 | LAM 100 mg/d and ADV 10 mg/d or ETV 0.5 mg/d | 96 | Ultrasound | 8 | Chen et al. [15] | 2006–2012 | China | 141 | 141 | Yes | Yes | 96 | ETV 0.5 mg/d | 96 | Ultrasound | 7 | Gong et al. [17] | 2010–2013 | China | 97 | 89 | No | Yes | 96 | Peg-IFN alfa-2a 180 μg/week | 48 | Histopathology | 6 | Xu et al. [20] | 2005–2009 | China | 50 | 50 | Yes | No | 48 | Peg-IFN alfa-2a 180 μg/week | 48 | Histopathology | 6 |
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