Review Article

The Effect of Hepatosteatosis on Response to Antiviral Treatment in Patients with Chronic Hepatitis B: A Meta-Analysis

Table 1

Characteristics of the studies included in this meta-analysis.

StudyYearLocationSample sizeNumber
included in
the analysis
Age-matchedSex-matchedFollow-up
(weeks)
Therapy regimenTherapy periodDiagnosis methodQuality scores

Cindoruk et al. [16]2002–2006Turkey14098YesYes48Peg-IFN alfa-2a
180 μg/week or
Peg-IFN alfa-2b
80 μg/week and
LAM 100 mg/d
48Histopathology7
Ates et al. [13]2006–2009Turkey8484NoYes96Peg-IFN alfa-2a
180 μg/week or
Peg-IFN alfa-2b
80 μg/week
48Histopathology6
Shi et al. [19]2007-2008China12096NoYes48Peg-IFN alfa-2a
180 μg/week or
Peg-IFN alfa-2b
80 μg/week
48Histopathology6
Jin et al. [18]2007–2009China267213YesYes96ETV 0.5 mg/d96Ultrasound9
Chen et al. [14]2007–2009China332316YesYes96LAM 100 mg/d and
ADV 10 mg/d or
ETV 0.5 mg/d
96Ultrasound8
Chen et al. [15]2006–2012China141141YesYes96ETV 0.5 mg/d96Ultrasound7
Gong et al. [17]2010–2013China9789NoYes96Peg-IFN alfa-2a
180 μg/week
48Histopathology6
Xu et al. [20]2005–2009China5050YesNo48Peg-IFN alfa-2a
180 μg/week
48Histopathology6