Adjuvant Second-Dose Chemotherapy before Surgery for Patients with Locally Advanced Rectal Malignancy Is Not Beneficial: A Systematic Review and Meta-Analysis

Table 2

Risk of bias in the prospective randomized controlled studies.

Study	Adequate random sequence generation	Allocation concealment	Blinding of participants and personnel	Incomplete outcome data	Selective outcome reporting	Other biases
Fernández-Martos et al. [16]	Yes	No	Yes	Yes	Yes	Yes
Marechal et al. [30]	Yes	No	Yes	Yes	Yes	Yes
Moore et al. [31]	No	No	Yes	Yes	Yes	Yes