The Role of Endoscopic Ultrasound in the Diagnosis and Management of Primary Gastric Lymphoma

Table 1

Comparison of Ann Arbor, Lugano, and Paris (TNM) classification systems.

Ann Arbor staging system		Lugano classification	Paris classification (TNM)	Lymphoma extension
IE1	Confined to mucosa, submucosa	Stage I	T1–T3N0M0	Confined to GI tract (mucosa, submucosa, muscularis propria, and serosa)
IE2	Confined to the stomach, invasion of the muscularis and/or serosa
IIE1	Involvement of the stomach and contiguous lymph nodes	Stage II; II1: local nodal involvement; II2: distant nodal involvement	T1–T3N1M0; T1–T3N2M0	Extending into the abdomen
IIE2	Involvement of the stomach and noncontiguous subdiaphragmatic lymph nodes			Perigastric lymph nodes
				More distant regional lymph nodes
IIIE	Involvement of the stomach and lymph nodes on both sides of the diaphragm	Stage III	T4N0M0	Penetrating of serosa and adjacent organs
			T1–T4N3M0	Lymph nodes on both sides of the diaphragm
IVE	Hematogenous spread	Stage IV	T1–T4N0–N3M1	Distant metastasis (e.g., bone marrow)