From Pathogenesis, Clinical Manifestation, and Diagnosis to Treatment: An Overview on Autoimmune Pancreatitis

Table 4

Comparisons of diagnostic criteria in different countries.

Diagnostic criteria	Japanese criteria(2006) [55]	SIHORts (2006) [57]	Korean criteria (2007) [56]	Asian criteria (2008) [58]
A: imaging	Diffuse or segmental narrowing of the MPD; diffuse or localized enlargement of the pancreas	Typical imaging features: diffusely enlarged gland with delayed (rim) enhancement; diffusely irregular and attenuated MPD; Atypical imaging features: focal pancreatic mass, focal pancreatic duct stricture	Diffuse enlargement of pancreas and diffuse or segmental irregular narrowing of MPD	Typical imaging features: diffusely enlarged gland with delayed (rim) enhancement; diffusely irregular and attenuated MPD; Atypical imaging features: focal pancreatic mass, focal pancreatic duct stricture
B: serology	High serum γ globulin, IgG, IgG4, or the presence of autoantibodies	Elevated serum IgG4 level	Elevated levels of IgG and/or IgG4 or detected autoantibodies	High level of serum IgG or IgG4 or detected autoantibodies
C: histology	Infiltration of lymphocytes and plasma cells	Lymphoplasmacytic infiltrate with storiform fibrosis showing abundant	Fibrosis and lymphoplasmacytic infiltration	Lymphoplasmacytic infiltration with fibrosis, with abundant; IgG4-positive cell infiltration
		(>10 cells/HPF) IgG4-positive cells
D: other organ involvement	Not included	Biliary stricture, parotid/lacrimal gland involvement, mediastinal lymphadenopathy, retroperitoneal fibrosis	Included	Not included
E: steroid effect	Not included	Included	Included	Included
Definite diagnosis	Criterion A + B; Criterion A + C	Criterion A + B; Criterion A + C; Criterion A + D; Criterion A + E	Criterion A + B; Criterion A + C; Criterion A + D; Criterion A + E	Criterion A + B; Criterion A + C; Histology shows the presence of lymphoplasmacytic sclerosing pancreatitis in the resected pancreas