Procalcitonin-Guided Antibiotics after Surgery for Peritonitis: A Randomized Controlled Study
Table 4
Secondary outcome measures.
Procalcitonin
Control
value
All (n = 79)
Subgroup 1 (n = 31)
All (n = 83)
Subgroup 1 (n = 33)
All
Subgroup 1
Duration of hospitalization, d
10 (5–24)
10 (6–24)
8 (4–16)
10 (6–20)
0.188
0.809
Reintroduction of antibiotics
6 (7.7%)
3 (10%)
5 (6.1%)
1 (3%)
0.762
0.340
Reoperation
24 (30.4%)
6 (19.4%)
20 (24.1%)
7 (21.1%)
0.383
1.00
Relavage abdominal cavity
10 (12.7%)
2 (6.5%)
7 (8.4%)
3 (9.1%)
0.447
1.00
Rehospitalization
5 (6.6%)
1 (3.6%)
5 (6.1%)
2 (6.1%)
1.00
1.00
Positive blood cultures
2 (2.5%)
0
3 (3.6%)
2 (6.1%)
1.00
0.493
Intra-abdominal abscess
14 (17.7%)
3 (9.7%)
14 (16.9%)
3 (9.1%)
1.00
1.00
Wound infection
17 (21.5%)
7 (22.6%)
15 (18.1%)
11 (33.3%)
0.694
0.410
Septic shock
4 (5.1%)
1 (3.2%)
4 (4.8%)
3 (9.1%)
1.00
0.614
Anastomotic leakage
3 (3.8%)
1 (3.2%)
3 (3.6%)
2 (6.1%)
1.00
1.00
Urinary infection
3 (3.8%)
2 (6.5%)
1 (1.2%)
0
0.358
0.231
Pneumonia
2 (2.5%)
0
4 (4.8%)
3 (9.1%)
0.682
0.239
Mortality
3 (3.8%)
3 (9.7%)
4 (4.9%)
3 (9.4%)
1.00
1.00
Duration of antibiotics and duration of hospitalization are medians with interquartile range (days). All other parameters are numbers with percentages.
