Diagnostic Value of Neutrophil-to-Lymphocyte Ratio and Platelet-to-Lymphocyte Ratio in Crohn’s Disease

Table 3

Accuracy of neutrophil-to-lymphocyte ratio (NLR) and other inflammatory markers in differentiating Crohn’s disease (CD) patients from healthy controls.

Parameters	CD group versus control group
	AUCs	Cutoffs	Sensitivity (%)	Specificity (%)	PPV (%)	NPV (%)	Overall accuracy (%)
Lymphocyte	0.28	2.69	5.00%	97.50%	66.67%	50.65%	51.25%
Platelet	0.77	242.50	53.30%	91.10%	85.69%	66.11%	72.20%
Neutrophil-to-lymphocyte ratio	0.74	2.72	68.30%	75.90%	73.92%	70.54%	72.10%
Neutrophil-to-monocyte ratio	0.47	10.61	31.70%	82.30%	64.17%	54.65%	57.00%
Lymphocyte-to-monocyte ratio	0.25	6.57	6.70%	97.50%	72.83%	51.10%	52.10%
Platelet-to-lymphocyte ratio	0.86	132.88	76.70%	84.80%	83.46%	78.45%	80.75%

The italics indicates comparisons with significant differences. PPV: positive predictive value; NPV: negative predictive value.