Clinical Study
Comparison of Esophageal Function Tests in Chinese Patients with Functional Heartburn and Reflux Hypersensitivity
Table 1
Demographic data and high-resolution manometry and impedance results.
| Items | FH | RH | Independent samples t-test, chi-square test, or Fisher’s exact test | HV | ANOVA, chi-square test, or Fisher’s exact test | | | |
| Age (mean ± SD, years) | 57.5 ± 47.0 | 51.0 ± 12.8 | | 54.8 ± 12.3 | | Male/female (n) | 56/91 | 43/48 | | 16/20 | | Dysphagia (n, %) | 5 (3.4) | 1 (1.0) | | 0 (0) | | Belching (n, %) | 12 (8.1) | 25 (27.4) | | 2 (5.5) | | Globus (n, %) | 13 (8.8) | 4 (4.3) | | 1 (2.7) | | Chest pain (n, %) | 24 (16.3) | 10 (10.9) | | 0 (0) | | Upper abdominal pain (n, %) | 8 (5.4) | 4 (4.3) | | 3 (8.3) | | Abdominal distension (n, %) | 5 (3.4) | 1 (1.0) | | 2 (5.5) | | LESP (mean ± SD, mmHg) | 17.3 ± 10.3 | 17.1 ± 10.5 | | 22.1 ± 9.4 | | LESL (mean ± SD, cm) | 3.8 ± 0.9 | 3.7 ± 0.7 | | 3.9 ± 0.9 | | LESRP (mean ± SD, mmHg) | 5.2 ± 4.6 | 4.5 ± 4.2 | | 5.7 ± 4.3 | | IRP (mean ± SD, mmHg) | 8.1 ± 4.7 | 7.9 ± 5.2 | | 7.3 ± 4.5 | | UESP (mean ± SD, mmHg) | 82.8 ± 31.5 | 81.7 ± 35.9 | | 88.8 ± 36.3 | | DEA (mean ± SD, mmHg) | 68.3 ± 30.5 | 61.9 ± 26.2 | | 78.3 ± 36.4 | | DCI (mean ± SD, mmHg·s·cm) | 806.3 ± 752.5 | 575.7 ± 495.1 | | 1060.0 ± 635.5 | | Ineffective esophageal motility (n (%)) | 40 (27.2) | 38 (41.7) | | 0 (0) | | Fragmented peristalsis (n (%)) | 5 (3.4) | 9 (9.9) | | 0 (0) | | Total bolus transit time, s | 6.5 ± 1.4 | 6.5 ± 1.3 | | 6.2 ± 1.1 | | Complete bolus transit rate, % | 75.4 ± 30.9 | 72.7 ± 32.1 | | 94.7 ± 11.5 | | Hiatus hernia (n (%)) | 4 (2.7) | 8 (8.8) | | 1 (2.8) | |
|
|
HV: healthy volunteers; FH: functional heartburn; RH: reflux hypersensitivity; LESP: lower esophageal sphincter pressure; LESL: lower esophageal sphincter length; LESRP: lower esophageal sphincter residual pressure; IRP: integrated relaxation pressure; UESP: upper esophageal sphincter pressure; DEA: distal esophageal amplitude; DCI: distal contractile integral.
|