Gastroenterology Research and Practice / 2017 / Article / Tab 1 / Research Article
Association of Poor Differentiation or Positive Vertical Margin with Residual Disease in Patients with Subsequent Colectomy after Complete Macroscopic Endoscopic Resection of Early Colorectal Cancer Table 1 Clinicopathologic characteristics of patients who underwent colectomy after macroscopic complete endoscopic resection of early colorectal cancer (
).
Characteristics Value Age, years 60 (31–78) Men/women 102 (68.9)/46 (31.1) Tumor location Cecum and ascending colon 11 (7.4) Transverse colon 9 (6.1) Descending colon 6 (4.1) Sigmoid colon 71 (48.0) Rectum 51 (34.5) Size of tumor (histologically measured), mm 13 (4–52) Macroscopic form of tumor Pedunculated 32 (21.6) Semipedunculated 67 (45.3) Sessile or flat 49 (33.1) Endoscopic resection method EMR 141 (95.3) ESD 7 (4.7) En bloc resection 121 (81.8) Histologic differentiation Well 57 (38.5) Moderate 84 (56.8) Poor 3 (2.0) Mucinous 4 (2.7) Depth of invasion Mucosa 4 (2.7) Submucosa 144 (97.3) Submucosal invasion depth, μ m 2000 (300–7000) Lymphovascular invasion 30 (20.3) Positive/unknown vertical endoscopic resection margin 68 (48/20) (45.9) Positive/unknown lateral endoscopic resection margin 51 (31/20) (34.5) Reasons for subsequent colectomy Poorly differentiated/mucinous histology 7 (4.7) Positive or unknown vertical margin 68 (45.9) Positive or unknown lateral margin 51 (34.4) Lymphovascular invasion 30 (20.3) Submucosal invasion depth >1000 μ m 122 (82.4) Residual tumor in the colorectal wall on colectomy 6 (4.1) Lymph node metastasis on colectomy 10 (6.8)
EMR: endoscopic mucosal resection; ESD: endoscopic submucosal dissection. Values are median (range) or number (%).