Association of Poor Differentiation or Positive Vertical Margin with Residual Disease in Patients with Subsequent Colectomy after Complete Macroscopic Endoscopic Resection of Early Colorectal Cancer

Table 2

Comparison between patients with and those without residual disease (residual tumor in the wall or lymph node metastasis) on colectomy.

Variable	No residual disease ()	Residual disease ()	value
Age, years	60 (35–78)	59 (31–74)	0.889
Men/women	93 (70.5)/39 (29.5)	9 (56.3)/7 (43.7)	0.262
Tumor location			0.530
Cecum and ascending colon	11 (8.3)	0
Transverse colon	8 (6.1)	1 (6.3)
Descending colon	4 (3.0)	2 (12.5)
Sigmoid colon	63 (47.7)	8 (50.0)
Rectum	46 (34.8)	5 (31.3))
Size of tumor (histologically measured), mm	13 (4–52)	15 (8–34)	0.682
Macroscopic form of tumor			0.059
Pedunculated	32 (24.2)	0
Semipedunculated	59 (44.7)	8 (50.0)
Sessile or flat	41 (31.1)	8 (50.0)
En bloc resection	108 (81.8)	13 (81.2)	1.0
Differentiation			0.028
Well/moderate	128 (97.0)	13 (81.2)
Poor/mucinous	4 (1/3) (3.0)	3 (2/1) (18.8)
Submucosal invasion depth, μm	1800 (300–7000)	2000 (800–4000)	0.342
Lymphovascular invasion	25 (18.9)	5 (31.2)	0.320
Positive/unknown vertical endoscopic resection margin	57 (41/16) (43.2)	11 (7/4) (68.8)	0.047
Positive/unknown lateral endoscopic resection margin	43 (26/17) (32.6)	8 (5/3) (50.0)	0.166

Values are median (range) or number (%).