Association of Poor Differentiation or Positive Vertical Margin with Residual Disease in Patients with Subsequent Colectomy after Complete Macroscopic Endoscopic Resection of Early Colorectal Cancer
Table 3
Univariate and multivariate analyses of factors associated with residual disease (residual tumor in the wall or lymph node metastasis) on colectomy.
Variables
Univariate OR (95% CI)
value
Multivariate OR (95% CI)
value
Age, years
0.996 (0.945–1.050)
0.888
Men
0.539 (0.188–1.550)
0.252
Right-sided colonic location
0.396 (0.049–3.179)
0.384
Tumor size
1.013 (0.954–1.075)
0.680
Sessile type
2.220 (0.779–6.324)
0.136
Piecemeal resection
0.963 (0.254–3.645)
0.956
Poor/mucinous histology (versus well/moderate)
7.385 (1.488–36.64)
0.014
7.508 (1.476–38.19)
0.015
Submucosal invasion depth
1.000 (1.000-1.001)
0.342
Deep submucosal invasion†
1.091 (0.128–9.274)
0.936
Lymphovascular invasion
0.514 (0.164–1.612)
0.254
Positive or unknown vertical margin
1.979 (1.005–3.898)
0.048
2.048 (1.003–4.178)
0.049
Positive or unknown lateral margin
1.493 (0.778–2.868)
0.228
Right-sided tumor location includes the cecum, ascending colon, and transverse colon. †Deep submucosal invasion means a submucosal invasion depth of >1000 μm. OR: odds ratio; CI: confidence interval.
