Review Article

The Best Anticoagulation Strategy for Cirrhotic Patients who Underwent Splenectomy: A Network Meta-Analysis

Table 3

The network meta-analysis results for different anticoagulation strategies based on consistency and inconsistency model.

ModelComparisons [Hazard ratio (95% CI)]

ConsistencyAlprostadil0.10 (0.00, 6.99)8.45 (0.77, 128.17)2.38 (0.06, 145.00)3.71 (0.16, 103.40)1.00 (0.03, 31.40)1.35 (0.02, 114.76)0.19 (0.00, 25.68)2.81 (0.15, 62.37)
9.99 (0.14, 1130.26)Antithrombin III93.90 (2.49, 4813.16)24.40 (3.99, 472.28)39.22 (0.65, 2745.33)10.29 (0.88, 259.54)13.86 (0.93, 390.27)1.95 (0.09, 74.70)27.86 (1.21, 1225.95)
0.12 (0.01, 1.31)0.01 (0.00, 0.40)Aspirin0.29 (0.02, 6.31)0.44 (0.06, 3.10)0.12 (0.01, 1.37)0.15 (0.01, 6.56)0.02 (0.00, 1.17)0.32 (0.08, 1.37)
0.42 (0.01, 16.82)0.04 (0.00, 0.25)3.40 (0.16, 59.56)Control1.57 (0.03, 45.04)0.40 (0.07, 1.90)0.52 (0.06, 4.15)0.07 (0.01, 0.80)1.14 (0.09, 13.08)
0.27 (0.01, 6.27)0.03 (0.00, 1.54)2.26 (0.32, 17.81)0.64 (0.02, 28.71)LMWH + Aspirin0.27 (0.01, 6.57)0.34 (0.01, 25.01)0.05 (0.00, 4.25)0.74 (0.06, 8.66)
1.00 (0.03, 32.11)0.10 (0.00, 1.14)8.38 (0.73, 96.72)2.49 (0.53, 13.85)3.71 (0.15, 84.20)LMWH + Warfarin1.22 (0.10, 18.36)0.19 (0.01, 3.62)2.68 (0.38, 19.60)
0.74 (0.01, 53.43)0.07 (0.00, 1.07)6.88 (0.15, 194.88)1.92 (0.24, 16.24)2.98 (0.04, 138.71)0.82 (0.05, 9.98)LMWH + Warfarin + Aspirin0.14 (0.01, 3.53)2.18 (0.08, 49.88)
5.31 (0.04, 447.86)0.51 (0.01, 10.55)48.41 (0.85, 1800.44)13.46 (1.25, 176.53)21.07 (0.24, 1149.69)5.34 (0.28, 106.06)7.25 (0.28, 191.30)Urokinase + Aspirin15.47 (0.43, 443.76)
0.36 (0.02, 6.50)0.04 (0.00, 0.83)3.08 (0.73, 13.31)0.88 (0.08, 11.67)1.36 (0.12, 15.82)0.37 (0.05, 2.63)0.46 (0.02, 12.69)0.06 (0.00, 2.33)Warfarin

InconsistencyAlprostadil0.10 (0.00, 7.41)7.36 (0.72, 105.37)2.44 (0.05, 132.85)3.23 (0.17, 77.61)0.95 (0.03, 33.79)1.34 (0.01, 119.83)0.18 (0.00, 19.28)2.51 (0.15, 52.78)
9.53 (0.13, 958.69)Antithrombin III73.89 (2.45, 3679.52)22.88 (3.65, 271.11)33.18 (0.75, 2209.94)8.93 (0.76, 174.82)12.20 (0.71, 306.30)1.98 (0.05, 51.21)25.30 (1.09, 867.87)
0.14 (0.01, 1.38)0.01 (0.00, 0.41)Aspirin0.31 (0.02, 6.14)0.44 (0.06, 3.09)0.12 (0.01, 1.38)0.17 (0.00, 6.45)0.02 (0.00, 1.21)0.33 (0.07, 1.50)
0.41 (0.01, 19.75)0.04 (0.00, 0.27)3.19 (0.16, 64.38)Control1.42 (0.04, 46.67)0.39 (0.07, 2.11)0.52 (0.06, 4.62)0.08 (0.01, 0.85)1.07 (0.08, 13.98)
0.31 (0.01, 6.03)0.03 (0.00, 1.33)2.27 (0.32, 16.51)0.70 (0.02, 23.27)LMWH + Aspirin0.28 (0.01, 6.36)0.37 (0.01, 23.66)0.06 (0.00, 4.16)0.76 (0.06, 8.86)
1.05 (0.03, 31.79)0.11 (0.01, 1.32)8.08 (0.73, 97.15)2.59 (0.47, 14.36)3.53 (0.16, 81.97)LMWH + Warfarin1.35 (0.08, 19.12)0.20 (0.01, 3.98)2.70 (0.37, 19.49)
0.75 (0.01, 72.23)0.08 (0.00, 1.41)6.01 (0.15, 289.21)1.90 (0.22, 17.38)2.68 (0.04, 175.22)0.74 (0.05, 11.94)LMWH + Warfarin + Aspirin0.15 (0.00, 4.10)1.95 (0.07, 66.30)
5.47 (0.05, 514.46)0.50 (0.02, 18.67)40.04 (0.82, 2003.35)12.68 (1.18, 184.57)17.65 (0.24, 1362.70)5.04 (0.25, 112.25)6.69 (0.24, 204.67)Urokinase + Aspirin13.57 (0.38, 497.85)
0.40 (0.02, 6.53)0.04 (0.00, 0.92)3.01 (0.66, 13.67)0.94 (0.07, 12.23)1.32 (0.11, 15.48)0.37 (0.05, 2.72)0.51 (0.02, 14.54)0.07 (0.00, 2.65)Warfarin