Clinical Study

Feasibility of Short-Period, High-Dose Intravenous Methylprednisolone for Preventing Stricture after Endoscopic Submucosal Dissection for Esophageal Cancer: A Preliminary Study

Table 3

Stricture cases administered steroid pulse therapy after esophageal ESD.

CaseSexAge (yr)LocationMucosal defect circumferenceLongitudinal resected specimen size (mm)DepthPeriod from ESD to stricture (days)No. of required EBDsEBD period(days)

1M67Mt≥7/845MM21314
2M78Lt≥3/4–<7/840LPM2111
3M76Mt≥7/870LPM15636
4M71Mt≥7/850EP1511
5M72Lt≥7/850EP15535
6M57Mt≥7/870EP14215

ESD: endoscopic submucosal dissection; EBD: endoscopic balloon dilation; Mt: middle thoracic esophagus; Lt: lower thoracic esophagus; EP: epithelium; LPM: lamina propria mucosa; MM: muscularis mucosa.