Gastroenterology Research and Practice / 2018 / Article / Tab 5 / Research Article
Prognostic Significance of Blood, Serum, and Ascites Parameters in Patients with Malignant Peritoneal Mesothelioma or Peritoneal Carcinomatosis Table 5 Univariate and multivariant analysis of the association between potential prognostic factors and survival for all 125 patients with malignant peritoneal effusions.
Prognostic factors Categories Patients (n ) Median survival time (months) (95% CI) valuea valueb Sex Male 49 8.0 (5.3–10.7) 0.131 Female 76 12.0 (8.9–15.1) Age (years) <67 80 11.0 (8.6–13.4) 0.528 ≥67 45 7.0 (3.5–10.4) Ascites glucose level (mmol/L) <5.2 65 11.0 (8.5–13.5) 0.770 ≥5.2 60 7.0 (1.7–12.3) Ascites albumin level (g/L) <28 65 8.0 (1.4–14.6) 0.990 ≥28 60 12.0(8.8–15.2) Ascites LDH level (U/L) <299 62 14.0 (11.79–16.25) 0.015 0.023 ≥299 63 7.0 (4.4–9.6) Ascites coenocyte numbers (%) <30 61 12 (11.0–13.0) 0.023 ≥30 64 7 (5.1–8.9) Ascites monocyte numbers (%) <70 55 7.0 (5.0–9.0) 0.207 ≥70 70 12.0 (11.1–12.9) Ascites coenocyte-to-monocyte ratio <0.43 64 12.0 (10.2–13.8) 0.019 ≥0.43 61 7.0 (5.0–9.0) Serum albumin level (g/L) <34 59 8.0 (4.9–11.2) 0.220 ≥34 66 12.0 (9.6–14.4) Serum-ascites albumin gradient (g/L) <8.0 62 12.0 (9.1–14.9) 0.765 ≥8.0 63 12.0 (9.7–14.3) Serum LDH level (range) (U/L) <210.5 64 14.0 (11.2–16.8) 0.008 0.037 ≥210.5 61 7.0 (4.6–9.4) Ascites-serum LDH ratio <1.14 61 12.0 (6.7–17.3) 0.885 ≥1.14 64 12.0 (10.9–13.1) Blood neutrophil-to-lymphocyte ratio <3.62 62 12.0 (11.0–13.0) 0.027 ≥3.62 63 7.0 (3.0–11.1)
a Univariate analysis: Kaplan–Meier method; b multivariant analysis: Cox regression method.