Differential Effects of Three Techniques for Hepatic Vascular Exclusion during Resection for Liver Cirrhosis on Hepatic Ischemia-Reperfusion Injury in Rats

Figure 1

Graphical illustration of the three techniques for hepatic vascular occlusion during resection in the cirrhotic liver in rats. Hepatic cirrhosis was successfully induced in rats using a combination of alcohol and CCl₄, and the rats were subjected to three different techniques for hepatic vascular occlusion during liver resection. (a) The entire hepatic portal system including the portal vein, artery, and biliary system was exposed; (b) in the Pringle maneuver group, the blood inflow to the entire liver was blocked by clamping across the hepatoduodenal ligament; (c) in the hemihepatic vascular occlusion group, the left hepatic portal vein and middle artery were occluded, allowing the normal blood supply to reach the right hemiliver; (d) in the hepatic blood inflow occlusion without hemihepatic artery control group, the portal vein was interrupted without interrupting the hepatic artery.

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