Research Article
The Effect of Marital Status on Survival of Patients with Gastrointestinal Stromal Tumors: A SEER Database Analysis
Table 2
Univariate and multivariate survival analysis for evaluating the influence of marital status on CSS in SEER database.
| | | Univariate analysis | Multivariate analysis | Variable | 5-year CCS | Log-rank χ2 test | P | HR (95% CI) | P |
| Sex | | 21.361 | <0.001 | | | Male | 76.2% | | | Reference | | Female | 81.7% | | | 0.741 (0.658–0.834) | <0.001 | Age | | 67.660 | <0.001 | | | ≤60 | 83.1% | | | Reference | | >60 | 75.1% | | | 1.649 (1.461–1.861) | <0.001 | Race | | 7.697 | 0.021 | | | White | 79.1% | | | Reference | | Black | 76.6% | | | 0.968 (0.835–1.122) | 0.666 | Others | 80.0% | | | 0.877 (0.737–1.045) | 0.142 | Tumor site | | 80.258 | <0.001 | | | Stomach | 79.8% | | | Reference | | Small intestine | 80.1% | | | 1.018 (0.895–1.158) | 0.785 | Rectum | 84.0% | | | 0.841 (0.582–1.215) | 0.356 | Colon | 56.3% | | | 1.916 (1.344–2.732) | <0.001 | Others | 61.2% | | | 1.388 (1.133–1.700) | 0.002 | Tumor size | | 282.519 | <0.001 | | | ≤2 cm | 90.2% | | | Reference | | >2–5 cm | 92.8% | | | 0.714 (0.466–1.094) | 0.122 | >5–10 cm | 83.5% | | | 1.256 (0.846–1.866) | 0.259 | >10 cm | 70.8% | | | 1.752 (1.181–2.599) | 0.005 | Unknown | 68.7% | | | 1.945 (1.322–2.861) | 0.001 | Grade | | 197.472 | <0.001 | | | I/II | 91.2% | | | Reference | | III/IV | 62.0% | | | 2.965 (2.310–3.807) | <0.001 | Unknown | 78.2% | | | 1.547 (1.242–1.927) | <0.001 | SEER stage | | 792.340 | <0.001 | | | Localized | 89.4% | | | Reference | | Regional | 75.2% | | | 1.983 (1.675–2.348) | <0.001 | Distant | 52.0% | | | 2.952 (2.542–3.428) | <0.001 | Unknown | 76.0% | | | 1.594 (1.288–1.973) | <0.001 | Therapy | | 6161.438 | <0.001 | | | Surgery | 84.2% | | | Reference | | No surgery | 52.8% | | | 2.428 (2.121–2.779) | <0.001 | Unknown | 40.0% | | | 4.142 (1.703–10.075) | 0.002 | Marital status | | 60.533 | <0.001 | | | Married | 81.5% | | | Reference | | Widowed | 69.4% | | | 1.674 (1.411–1.986) | <0.001 | Single | 75.8% | | | 1.377 (1.183–1.602) | <0.001 | Divorced/separated | 78.1% | | | 1.233 (1.014–1.501) | 0.036 |
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Others include American Indian/Alaska Native, Asian/Pacific Islander, and unknown. NI: not included in the multivariate survival analysis. |