The Effect of Marital Status on Survival of Patients with Gastrointestinal Stromal Tumors: A SEER Database Analysis

Table 2

Univariate and multivariate survival analysis for evaluating the influence of marital status on CSS in SEER database.

		Univariate analysis		Multivariate analysis
Variable	5-year CCS	Log-rank χ^2 test	P	HR (95% CI)	P
Sex		21.361	<0.001
Male	76.2%			Reference
Female	81.7%			0.741 (0.658–0.834)	<0.001
Age		67.660	<0.001
≤60	83.1%			Reference
>60	75.1%			1.649 (1.461–1.861)	<0.001
Race		7.697	0.021
White	79.1%			Reference
Black	76.6%			0.968 (0.835–1.122)	0.666
Others	80.0%			0.877 (0.737–1.045)	0.142
Tumor site		80.258	<0.001
Stomach	79.8%			Reference
Small intestine	80.1%			1.018 (0.895–1.158)	0.785
Rectum	84.0%			0.841 (0.582–1.215)	0.356
Colon	56.3%			1.916 (1.344–2.732)	<0.001
Others	61.2%			1.388 (1.133–1.700)	0.002
Tumor size		282.519	<0.001
≤2 cm	90.2%			Reference
>2–5 cm	92.8%			0.714 (0.466–1.094)	0.122
>5–10 cm	83.5%			1.256 (0.846–1.866)	0.259
>10 cm	70.8%			1.752 (1.181–2.599)	0.005
Unknown	68.7%			1.945 (1.322–2.861)	0.001
Grade		197.472	<0.001
I/II	91.2%			Reference
III/IV	62.0%			2.965 (2.310–3.807)	<0.001
Unknown	78.2%			1.547 (1.242–1.927)	<0.001
SEER stage		792.340	<0.001
Localized	89.4%			Reference
Regional	75.2%			1.983 (1.675–2.348)	<0.001
Distant	52.0%			2.952 (2.542–3.428)	<0.001
Unknown	76.0%			1.594 (1.288–1.973)	<0.001
Therapy		6161.438	<0.001
Surgery	84.2%			Reference
No surgery	52.8%			2.428 (2.121–2.779)	<0.001
Unknown	40.0%			4.142 (1.703–10.075)	0.002
Marital status		60.533	<0.001
Married	81.5%			Reference
Widowed	69.4%			1.674 (1.411–1.986)	<0.001
Single	75.8%			1.377 (1.183–1.602)	<0.001
Divorced/separated	78.1%			1.233 (1.014–1.501)	0.036

Others include American Indian/Alaska Native, Asian/Pacific Islander, and unknown. NI: not included in the multivariate survival analysis.