Research Article
Factors Influencing Disability and Quality of Life during Treatment: A Cross-Sectional Study on IBD Patients
Table 1
Factors influencing IBD quality of life.
| | | Univariate analysis | Multivariate model: backward elimination | Variables | 435 | Unadjusted OR Risk of having pathological IBDQ (≤170) | Adjusted OR Risk of having pathological IBDQ (≤170) | Adjusted OR Risk of having pathological IBDQ (≤170) |
| Disease | | | | | CD | 203 | 1 | 1 | 1 | UC | 232 | 0.59 (0.40-0.88) | 0.44 (0.28-0.71) | 0.44 (0.28-0.70) | Age group | | | | | <45 | 189 | 1 | | | ≥45 | 246 | 1.19 (0.80-1.76) | | | Sex | | | | | Men | 231 | 1 | | | Women | 204 | 1.20 (0.81-1.76) | | | Disease latency | | | | | ≤1 year | 335 | 1 | | | >1 year | 100 | 1.03 (0.96-1.11) | | | Disease duration | | | | | ≤5 years | 80 | 1 | | | >5 years | 355 | 0.99 (0.97-1.01) | | | Current smoking status | | | | | Nonsmoker | 371 | 1 | | | Smoker | 64 | 0.17 (0.68-2.01) | | | Current alcohol intake | | | | | No | 189 | 1 | 1 | | Yes | 246 | 0.63 (0.42-0.92) | 0.69 (0.44-1.07) | | Disease active ( or ) | | | | | Inactive | 332 | 1 | 1 | 1 | Active | 103 | 5.62 (3.47-9.12) | 5.47 (3.11-9.61) | 5.67 (3.30-9.76) | High faecal calprotectin (>250) | | | | | No | 248 | 1 | 1 | | Yes | 187 | 1.90 (1.28-2.82) | 1.18 (0.74-1.87) | | Anaemia (, <13 males) | | | | | No | 373 | 1 | 1 | 1 | Yes | 62 | 2.69 (1.68-5.80) | 2.05 (1.09-3.86) | 2.15 (1.15-4.03) | UC localization | | | | | E1/E2 | 123 | 1 | | | E3 | 109 | 1.34 (0.77-2.33) | | | CD behavior | | | | | Nonstricturing, nonpenetrating | 104 | 1 | | | Stricturing | 65 | 1.01 (0.54-1.89) | | | Penetrating | 34 | 1.26 (0.58-2.73) | | | Localization | | | | | L1 terminal ileum | 48 | 1 | | | L2 colon or L3 ileocolon | 148 | 1.19 (0.61-2/29) | | | L4 upper or upper+other | 7 | 1.86 (0.37-9.27) | | | Extraintestinal manifestations | | | | | No | 326 | 1 | 1 | 1 | Yes | 109 | 3.89 (2.47-6.14) | 3.08 (1.87-5.08) | 3.15 (1.92-5.18) | Immunosuppressant | | | | | No | 381 | 1 | | | Yes | 54 | 1.19 (0.67-2.12) | | | Biologics | | | | | No | 262 | 1 | | | Yes | 173 | 1.42 (0.96-2.10) | | | Surgery | | | | | No | 320 | 1 | | | Yes | 115 | 1.36 (0.88-2.10) | | |
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