Research Article
Factors Influencing Disability and Quality of Life during Treatment: A Cross-Sectional Study on IBD Patients
Table 2
Factors influencing IBD-Disability Index.
| | | Univariate analysis | Multivariate model: backward elimination | Variables | | Unadjusted OR Risk of having pathological IBD-DI (≤3.5) | Adjusted OR Risk of having pathological IBD-DI (≤3.5) | Adjusted OR Risk of having pathological IBD-DI (≤3.5) |
| Disease | | | | | CD | 203 | 1 | 1 | 1 | UC | 232 | 0.66 (0.45-0.97) | 0.52 (0.34-0.80) | 0.52 (0.34-0.80) | Age group | | | | | <45 | 189 | 1 | | | ≥45 | 246 | 1.25 (0.85-1.83) | | | Sex | | | | | Men | 231 | 1 | | | Women | 204 | 1.26 (0.86-1.84) | | | Disease latency | | | | | ≤1 year | 335 | 1 | | | >1 year | 100 | 1.03 (0.95-1.11) | | | Disease duration | | | | | ≤5 years | 80 | 1 | | | >5 years | 355 | 1.00 (0.98-1.02) | | | Current smoking status | | | | | Nonsmoker | 371 | 1 | | | Smoker | 64 | 0.89 (0.52-1.52) | | | Current alcohol intake | | | | | No | 189 | 1 | 1 | | Yes | 246 | 0.63 (0.43-0.93) | 0.67 (0.44-1.02) | | Disease activity (pMayo or HBI) | | | | | Inactive | 332 | 1 | 1 | 1 | Active | 103 | 5.83 (3.41-9.95) | 5.61 (3.10-10.17) | 5.62 (3.16-9.98) | High faecal calprotectin (>250) | | | | | No | 248 | 1 | 1 | | Yes | 187 | 1.69 (1.15-2.48) | 1.07 (0.69-1.67) | | Anaemia (, <13 males) | | | | | No | 373 | 1 | 1 | 1 | Yes | 62 | 2.70 (1.50-4.85) | 1.88 (0.98-3.62) | 1.96 (1.02-3.73) | UC localization | | | | | E1/E2 | 123 | 1 | | | E3 | 109 | 1.29 (0.77-2.17) | | | CD behavior | | | | | Nonstricturing, nonpenetrating | 104 | 1 | | | Stricturing | 65 | 1.20 (0.64-2.25) | | | Penetrating | 34 | 1.22 (0.55-2.68) | | | Localization | | | | | L1 terminal ileum | 48 | 1 | | | L2 colon or L3 ileocolon | 148 | 1.42 (0.74-2.74) | | | L4 upper or upper+other | 7 | 0.74 (0.15-3.71) | | | Extraintestinal manifestations | | | | | No | 326 | 1 | 1 | 1 | Yes | 109 | 3.41 (2.12-5.48) | 2.66 (1.59-4.43) | 2.73 (1.65-4.53) | Immunosuppressant | | | | | No | 381 | 1 | | | Yes | 54 | 1.35 (0.76-2.40) | | | Biologics | | | | | No | 262 | 1 | | | Yes | 173 | 1.31 (0.89-1.93) | | | Surgery | | | | | No | 320 | 1 | | | Yes | 115 | 1.50 (0.97-2.31) | | |
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