Gastroenterology Research and Practice

Colorectal Cancer Screening


Publishing date
15 Feb 2012
Status
Published
Submission deadline
15 Aug 2011

1Department of Gastroenterology, University Hospital of the Canary Islands, La Laguna University School of Medicine, 38320 Tenerife, Spain

2Gastrointestinal Endoscopy Division, National Cancer Center Hospital, Tokyo 104-0045, Japan

3Department of Gastroenterology and Digestive Endoscopy, Nuovo Regina Margherita Hospital, 00153 Rome, Italy

4SCDU Epidemiologia dei Tumori, Azienda Ospedaliero-Universitaria San Giovanni Battista di Torino, 10126 Torino, Italy


Colorectal Cancer Screening

Description

Colorectal cancer (CRC) is the most common malignancy worldwide if men and women are considered together, with more than 1,200,000 new cases per year. In addition, it represents the second leading cause of cancer-related death.

CRC can be preventable as more than 85% of tumors arise in a premalignant polyp. Therefore, the aim of CRC screening is to reduce mortality by identifying individuals with presymptomatic neoplastic lesions who may require further examination and treatment. Screening tests should be workable, unexpensive, acceptable, sensitive, specific, and safe. However, none of the available recommended tests (fecal occult blood test (FOBT), sigmoidoscopy, colonoscopy, computed tomographic colonography, and faecal DNA analysis) fulfil these premises. By contrast, in first-degree relatives of patients with CRC, colonoscopy is empirically recommended from age 40 or 10 years before the age of the diagnosis of the youngest relative.

Compliance is one of the main factors influencing the success of any population-based screening program. If the test is too complicated to perform or not easily accepted by the target population, screening uptake will be poor and the effectiveness of the program will be low. In fact, this is a relevant drawback in many CRC screening programs running worldwide, with compliance rates between 25% and 67%.

The focus of this special issue will be on the different aspects related to CRC screening among average and familial-risk populations. We are interested in articles (original research papers, meta-analysis, and reviews) regarding the accuracy of noninvasive tests for detecting significant colorectal neoplasms, clinical trials comparing different screening strategies, awareness of the risk populations to be screened, barriers to CRC screening, and quality of the screening process. Potential topics include, but are not limited to:

  • Diagnostic yield and optimization of screening with immunochemical FOBT and structural tests for detecting significant colorectal neoplasms
  • Novel serological biomarkers and faecal DNA markers for early CRC detection
  • New endoscopic techniques for improving the diagnostic yield of colorectal adenomas
  • Cost-effectiveness of screening for CRC
  • Knowledge, attitudes, and barriers regarding CRC screening
  • Organizational aspects of population-based screening programs
  • Risk factors for significant colorectal neoplasms in the familial-risk population
  • Screening policy in the familial-risk population
  • Postpolypectomy surveillance
  • Quality of screening colonoscopy

Before submission authors should carefully read over the journal's Author Guidelines, which are located at http://www.hindawi.com/journals/grp/guidelines/. Prospective authors should submit an electronic copy of their complete manuscript through the journal Manuscript Tracking System at http://mts.hindawi.com/ according to the following timetable:


Articles

  • Special Issue
  • - Volume 2012
  • - Article ID 476065
  • - Editorial

Colorectal Cancer Screening

Enrique Quintero | Yutaka Saito | ... | Carlo Senore
  • Special Issue
  • - Volume 2012
  • - Article ID 846985
  • - Review Article

Progress and Challenges in Colorectal Cancer Screening

Enrique Quintero | Cesare Hassan | ... | Yutaka Saito
  • Special Issue
  • - Volume 2012
  • - Article ID 638391
  • - Research Article

Visualization of Laterally Spreading Colorectal Tumors by Using Image-Enhanced Endoscopy

Naoto Tamai | Yutaka Saito | ... | Hisao Tajiri
  • Special Issue
  • - Volume 2012
  • - Article ID 728454
  • - Clinical Study

Cost-Effectiveness of Total Colonoscopy in Screening of Colorectal Cancer in Japan

Masau Sekiguchi | Takahisa Matsuda | ... | Yutaka Saito
  • Special Issue
  • - Volume 2012
  • - Article ID 895807
  • - Research Article

What Would Make Getting Colorectal Cancer Screening Easier? Perspectives from Screeners and Nonscreeners

Gilda G. Medina | Amy McQueen | ... | Sally W. Vernon
  • Special Issue
  • - Volume 2012
  • - Article ID 971383
  • - Review Article

Application of Autofluorescence Endoscopy for Colorectal Cancer Screening: Rationale and an Update

Hiroyuki Aihara | Hisao Tajiri | Takeshi Suzuki
  • Special Issue
  • - Volume 2012
  • - Article ID 483417
  • - Review Article

Factors Influencing Colorectal Cancer Screening Participation

Antonio Z. Gimeno García
  • Special Issue
  • - Volume 2012
  • - Article ID 184343
  • - Review Article

Fecal Molecular Markers for Colorectal Cancer Screening

Rani Kanthan | Jenna-Lynn Senger | Selliah Chandra Kanthan
Gastroenterology Research and Practice
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Acceptance rate5%
Submission to final decision98 days
Acceptance to publication22 days
CiteScore3.900
Journal Citation Indicator0.370
Impact Factor2.0
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