Biliary Epithelial Apoptosis, Autophagy, and Senescence in Primary Biliary Cirrhosis

<table>Possible regulation of microenvironment by senescent BECs expressing SASPs such as chemokines and cytokines in PBC. Senescent BECs may participate in modulation of the inflammatory microenvironment by recruiting monocytes and possibly other types of inflammatory cells, induction of senescence in surrounding cells, and progression of fibrosis via SASP.</table>

Hepatitis Research and Treatment

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Figure 4

Figure 4: Biliary Epithelial Apoptosis, Autophagy, and Senescence in Primary Biliary Cirrhosis 