Clinical Study

Tumor Necrosis Factor Receptor 1 Expression Is Upregulated in Dendritic Cells in Patients with Chronic HCV Who Respond to Therapy

Figure 1

TNFR1 and TNFR2 mRNA levels were not different between HCV( )/ALD/NAFLD control patients and genotype 1  patients prior to treatment. TNFR1 mRNA levels of PBMC’s isolated from 10 HCV( ) controls, 11 ALD/NAFLD controls, and 23 HCV+ patients prior to therapy were ascertained by real time PCR (Panel A). TNFR2 mRNA levels of PBMC’s isolated from 10 HCV( ) controls, 5 ALD/NAFLD controls, and 18 patients prior to therapy were ascertained by real time PCR (Panel B). Statistical differences were assessed by - test.
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(a)
429243.fig.001b
(b)