Evolution of Hepatitis B Virus in a Chronic HBV-Infected Patient over 2 Years

Figure 1

Partial nucleotide sequences of all the 26 clones obtained from three time points. Black bars indicate the major mutation during this period of time. The variants include nucleotide substitution and deletion. 602 (1st time point, 1 day); 6022 (2nd time point, 6 months); 6023 (3rd time point, 31 months).