Evolution of Hepatitis B Virus in a Chronic HBV-Infected Patient over 2 Years

Figure 3

HBV spliced variants. There were 15 types of splicer reported in the literature, including seven 5′-splice sites at nucleotide positions 2447, 2067, 2985, 3018, 2087, 2471, 458; six 3′-splice sites at nucleotide positions 489, 2350, 2902, 2935, 282, 1308. In this report, 3 new splicers were detected, including two new 5′–splice donors (nt3144 and 3024) and three new 3′-splice acceptors (nt56, 3193, and 3202).