Hepatitis C Virus: A Critical Appraisal of New Approaches to Therapy

Table 5

Responses in treatment-experienced patients.

	Boceprevir (BOC)		Telaprevir (T)
	Experienced		Experienced
	RESPOND-2 [7] LI + BOC RGT + BOC/PR48 (ITT)		REALIZE [8] T12/PR48 + LI + T12/PR48 (ITT)
Overall rates, %	Partial responder	Relapser	Null responder	Partial responder	Relapser
SVR	46	72	31	57	86
Relapse	13		26	23	7
Any adverse events, %	100		98
Rash	15		37
Anemia	44		33
Discontinuation due to adverse events	10		13

LI: lead-in; RGT: response-guided therapy; ITT: intention to treat.