Circulating Cytokines and Histological Liver Damage in Chronic Hepatitis B Infection

Table 3

Multivariate analyses of the association between degrees of necroinflammation and other parameters.

Parameters	Standardized; coefficients	𝑃 value
Age	−0.13	0.51
BMI	0.02	0.93
ALT	0.38	0.13
HBV DNA	0.07	0.82
HBsAg titer	−0.16	0.6
IL-2	−0.38	0.19
IL-4	0.35	0.51
IL-5	0.16	0.66
IL-10	0.96	0.04*
IL-12p70	−1.69	0.06
IL-13	0.67	0.16
GMCSF	−0.70	0.18
IFN-gamma	0.27	0.48
TNF-alpha	0.76	0.09

∗Statistically significant.