Neither MICA Nor DEPDC5 Genetic Polymorphisms Correlate with Hepatocellular Carcinoma Recurrence following Hepatectomy
Table 2
Data among HCV-positive patients who underwent hepatectomy for HCC carrying GG, GA, and AA allele at rs1012068 (DEPDC5).
rs1012068
TT
TG/GG
value
Age (y), mean ± SD
69 ±1
71 ± 2
n.s
Sex (male/female),
38/12
12/2
n.s
Platelet count (×104/L), mean ± SD
13.5 ± 0.8
15.1 ± 1.5
n.s
Total bilirubin level (mg/dL), mean ± SD
0.9 ± 0.07
0.9 ± 0.1
n.s
Prothrombin time (%), mean ± SD
0/11/10
0/1/7
n.s
ICGR15 (%), mean ± SD
16.5 ± 1.4
15.7 ± 2.2
n.s
Operative time (min), mean ± SD
344 ± 15
357 ± 29
n.s
Intraoperative bleeding (mL), mean ± SD
631 ± 75
817 ± 146
n.s
Maximum tumor size (cm), mean ± SD
3.4 ± 0.5
4.0 ± 0.6
n.s
AFP level (ng/mL), mean (minimum–maximum)
2004 (2.0–5846)
250 (5.5–17156)
n.s
DCP level (mAU/mL), mean (minimum–maximum)
2429 (10–46561)
1348 (9–15526)
n.s
Stage (I/II/III/IV),
7/28/14/1
3/8/3/0
n.s
Tumor differentiation (well/moderate /poorly),
11/35/4
3/8/3
n.s
Fibrosis stage (F0-2/F3-4),
19/31
8/6
<0.05
AFP: alpha-fetoprotein, DCP: des-gamma-carboxy prothrombin, HCC: hepatocellular carcinoma, ICGR15: indocyanin green retention at 15 minutes, and n.s: not significant.
