Hepatocellular Adenoma: Evaluation with Contrast-Enhanced Ultrasound and MRI and Correlation with Pathologic and Phenotypic Classification in 26 Lesions
Table 3
Radiological (CEUS and MRI) features considering HCA subtype.
Inflammatory HCA (typical on imaging)
Inflammatory HCA (less typical on imaging)
Steatotic HCA
Atypical HCA
values*
CEUS
B mode
HypoE
3 (43%)
5 (56%)
0
1 (25%)
IsoE
2 (29%)
1 (11%)
1 (17%)
1 (25%)
0,2958
HyperE
2 (29%)
3 (33%)
5 (83%) (1 heterogeneous)
2 (50%)
Arterial enhancement
None
0
0
1 (17%)
0
Slight
0
3 (33%)
2 (33%)
2 (50%)
0,1514
Moderate
3 (43%)
3 (33%)
3 (50%)
0
Intense
4 (57%)
3 (33%)
0
2 (50%)
Delayed enhancement
Persistent
6 (86%)
0
0
2 (50%)
IsoE
1 (14%)
6 (67%)
3 (50%)
1 (25%)
0,0019
HypoE
0
3 (33%)
3 (50%)
1 (25%)
Homogeneousness enhancement
Homogeneous
7 (100%)
5 (56%)
5 (83%)
2 (50%)
0,0517
Heterogeneous
0
4 (44%)
1 had no enhancement
2 (50%)
Filling direction
Centripetal
6 (86%)
7 (78%)
1 (17%)
2 (50%)
0,1012
Indifferent
1 (14%)
2 (22%)
4 (67%)1 had no enhancement
2 (50%)
0,0273**
MRI
T1
HypoS
1 (14%)
3 (33%)
3 (50%)
1 (25%)
IsoS
4 (57%)
2 (22%)
3 (50%)
3 (75%)
0,2253
HyperS
2 (29%)
4 (33%)
0
0
IN/OUT
No drop out
7 (100%)
6 (67%)
0
2 (50%)
1,79E−04
Drop out
0
3 (44%)
6 (100%) included 1 heterogeneous
2 (50%) included 1 heterogeneous
T2
HypoS
7 (100%)
3 (33%)
3 (50%)
1 (25%)
IsoS
0
1 (11%)
1 (17%)
2 (50%)
0,1012
HyperS
0
5 (56%)
2 (33%)
1 (25%)
Arterial enhancement
None
0
0
1 (17%)
1 (25%)
Slight
0
2 (22%)
3 (50%)
0
0,0026
Moderate
0
2 (22%)
2 (33%)
2 (50%)
Intense
7 (100%)
5 (56%)
0
1 (25%)
Delayed phase
Persistent
6 (86%)
3 (33%)
0
2 (50%)
IsoS
1 (14%)
1 (11%)
0
0
0,005
HypoS
0
5 (56%)
6 (100%)
2 (50%)
*Test made with 4 categories of HCAs (inflammatory typical on imaging, inflamm less typical on imaging, steatotic and atypic),
**Test made with 3 categories of HCAs (inflammatory, steatotic and atypic).
