ICAM-1 Upregulation in Ethanol-Induced Fatty Murine Livers Promotes Injury and Sinusoidal Leukocyte Adherence after Transplantation
Figure 2
ALT release is decreased after transplantation of ICAM-1 deficient fatty livers. Serum ALT was assessed 8 h after sham operation (Sham) and 2 and 8 h after mouse liver transplantation (LT), as described in Section 2. Transplants were performed into WT recipients after ethanol treatment of wild type (WT) or ICAM-1 deficient (KO) liver donors. Sham groups had normal and comparable values to unoperated animals, and only sham is shown. Group sizes were sham WT and KO, 3; LT WT, 5; LT KO, 6. * versus KO grafts.
